RETURN OF OVARIAN FUNCTION FOLLOWING SPONTANEOUS ABORTION
| Autor: | M. L. Donnet, P. W. Howie, M. Marnie, Mark Lewis, W. Cooper |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Ovulation medicine.medical_specialty Time Factors Estrone Endocrinology Diabetes and Metabolism media_common.quotation_subject Physiology Abortion Biology Luteal phase Excretion Anovulation chemistry.chemical_compound Endocrinology Pregnancy Internal medicine Follicular phase medicine Humans Endocrine system Morning media_common business.industry Ovary Obstetrics and Gynecology General Medicine Luteinizing Hormone medicine.disease Abortion Spontaneous chemistry Pregnanediol Female business |
| Zdroj: | Clinical Endocrinology. 33:13-20 |
| ISSN: | 1365-2265 0300-0664 |
| DOI: | 10.1111/j.1365-2265.1990.tb00460.x |
| Popis: | Assays of first morning urine samples for oestrone-3-glucuronide, LH and pregnanediol-3-glucuronide, were used to study endocrine function and return to ovulation in 18 subjects following spontaneous miscarriage. On the basis of the endocrine data, ovulation occurred in all 18 women in the cycle prior to first menses at a mean of 29 days post-partum (range 13-103 days) with one subject conceiving in that cycle. Compared with the second cycle, the first cycle after spontaneous abortion had similar levels of follicular phase peak ovulatory oestrone excretion but lower levels during the late luteal phase (P less than 0.02), lower levels of peak LH (50.5 IU/g creatinine (C) cf. 68.8 IU/g C; P less than 0.04) and lower late secretory peak pregnanediol (4.6 mg/g C cf. 6.1 mg/g C; P less than 0.02). The mean luteal phase length of 12.9 days in the first cycle was shorter than the mean of 14.4 days in the second cycle (P less than 0.02). These data show that, although there is some disturbance of endocrine function in the first cycle after spontaneous abortion, the majority of women have a rapid return to ovulation, making the early use of contraception necessary for those wishing to avoid conception. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text