Neuroblastoma, retinoblastoma, and brain tumors in children
Autor: | Garrett M. Brodeur, R L Saylors rd |
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Rok vydání: | 1991 |
Předmět: |
Oncology
Cancer Research medicine.medical_specialty Central nervous system Genes myc Neuroblastoma Risk Factors Internal medicine medicine Humans Neurologic sequelae Child Mass screening Neoplasm Staging Retinoblastoma business.industry Brain Neoplasms Eye Neoplasms Gene Amplification Glioma medicine.disease medicine.anatomical_structure business Medulloblastoma |
Zdroj: | Current opinion in oncology. 3(3) |
ISSN: | 1040-8746 |
Popis: | Considerable progress has been made recently in the biologic understanding and the clinical management of pediatric tumors of the peripheral and central nervous system. Here we review important representative studies published primarily in the past 2 years regarding neuroblastoma, retinoblastoma, and brain tumors in children. Highlights include 1) the importance of tumor DNA content, N-myc amplification, and chromosome 1 deletion in predicting outcome of patients with neuroblastoma; 2) the impact of mass screening for neuroblastoma in Japan and elsewhere; 3) improvements in the clinical management of neuroblastoma, retinoblastoma, and brain tumors; and 4) neurologic sequelae of these tumors and their treatment. |
Databáze: | OpenAIRE |
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