Sinus Node Dysfunction in 128 Patients
Autor: | B L Nielsen, J S Nielsen, E Simonsen |
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Rok vydání: | 2009 |
Předmět: |
Adult
Male Pacemaker Artificial medicine.medical_specialty Heart disease Sinoatrial block Sinus bradycardia Embolism Bradycardia Internal Medicine medicine Humans Arrhythmia Sinus Sinus (anatomy) Aged Retrospective Studies Cause of death Medical treatment business.industry Systemic embolism Retrospective cohort study Middle Aged Prognosis medicine.disease Surgery medicine.anatomical_structure Sinoatrial Block Female medicine.symptom business Follow-Up Studies |
Zdroj: | Acta Medica Scandinavica. 208:343-348 |
ISSN: | 0001-6101 |
DOI: | 10.1111/j.0954-6820.1980.tb01210.x |
Popis: | A retrospective study covering all admissions during a 6-year period revealed 128 patients with sinus node dysfunction (SND). The patients were grouped according to the ECG criteria chosen: group I 33 patients with sinus bradycardia, group II 37 with sinoatrial block/sinus arrest, group III 58 with brady-tachy syndrome. Additional heart disease, predominantly ischaemic, was found in 56%. The frequency and severity of symptoms increased from group I to group III. Pacemaker treatment was given to 40% of the cases, while medical treatment alone was successful in 17%. A follow-up including 104 patients was carried out after a mean observation period of approximately three years. Sixteen patients had died. The cause of death may have been SND per se in only one case. Five patients died of apoplectic insults or complications to such. In total, nine possible or proven systemic embolic events were found--all occurring in patients with brady-tachy syndrome. A progression of the ECG abnormality from a lower to a higher group took place in nine patients during the observation period. It is concluded that SND is a condition with a broad clinical spectrum and a stationary or slowly progressive course. In general, it carries a good prognosis. A substantial number of deaths of disabilities in patients with brady-tachy syndrome may be ascribed to systemic embolism. Long-term anticoagulant therapy is proposed in this subgroup of patients with SND. |
Databáze: | OpenAIRE |
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