Preferences for herpes zoster vaccination among adults aged 50 years and older in the United States: results from a discrete choice experiment
Autor: | Kelley H. Myers, Christine Poulos, Brandon J. Patterson, Brennan Mange, Eric M Hillson, Alexandra Stewart |
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Rok vydání: | 2021 |
Předmět: |
0301 basic medicine
Research design Adult Immunology Logit Discrete choice experiment Herpes Zoster 03 medical and health sciences 0302 clinical medicine Drug Discovery Medicine Herpes Zoster Vaccine Humans 030212 general & internal medicine Aged Pharmacology Vaccines business.industry Cost sensitive Vaccination Middle Aged Latent class model United States 030104 developmental biology Preference weight Molecular Medicine business Demography |
Zdroj: | Expert review of vaccines. 20(6) |
ISSN: | 1744-8395 |
Popis: | BACKGROUND Most adults, and disproportionately fewer African-Americans, have not received herpes zoster (HZ) vaccination despite current recommendations. This study (GSK study identifiers: 208677/HO-17-18066) assessed HZ vaccination preferences among adults aged ≥ 50 years. RESEARCH DESIGN AND METHODS In this discrete choice experiment, respondents chose among a 'no vaccine' option and two HZ vaccine profiles, characterized by seven attributes, in a series of choice questions. Random-parameters logit results were used to predict likely vaccine uptake. Subgroup and latent class analysis of African-American's preferences were performed. RESULTS The preference weight for choosing HZ vaccines over no vaccine was statistically significant among the 1,454 respondents (71.9% whites; 25.2% African-Americans). Out-of-pocket (OOP) cost and vaccine effectiveness (VE) were the most important attributes. The African-American and the non-African-American subgroups had statistically significant differences in preferences (χ2 = 59.91, p |
Databáze: | OpenAIRE |
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