Piper betle-mediated synthesis, characterization, antibacterial and rat splenocyte cytotoxic effects of copper oxide nanoparticles
| Autor: | Kwang-Min Cho, Oh Byung-Taek, Cho Min, Loganathan Praburaman, Sengottaiyan Arumugam, Seralathan Kamala-Kannan, Koildhasan Manoharan, Jum-Suk Jang, Govarthanan Muthusamy |
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| Rok vydání: | 2015 |
| Předmět: |
Scanning electron microscope
Cell Survival Biomedical Engineering Analytical chemistry Pharmaceutical Science Medicine (miscellaneous) 02 engineering and technology 010402 general chemistry 01 natural sciences Rats Sprague-Dawley Splenocyte Animals Viability assay Cytotoxicity Cells Cultured Ralstonia solanacearum Piper biology Chemistry Cytotoxins Plant Extracts General Medicine 021001 nanoscience & nanotechnology biology.organism_classification 0104 chemical sciences Anti-Bacterial Agents Piper betle Rats Plant Leaves Transmission electron microscopy Xanthomonas axonopodis Nanoparticles 0210 nano-technology Antibacterial activity Copper Spleen Biotechnology Nuclear chemistry |
| Zdroj: | Artificial cells, nanomedicine, and biotechnology. 44(6) |
| ISSN: | 2169-141X |
| Popis: | The study reports a simple, inexpensive, and eco-friendly synthesis of copper oxide nanoparticles (CuONPs) using Piper betle leaf extract. Formation of CuONPs was confirmed by UV-visible spectroscopy at 280 nm. Transmission electron microscopy (TEM) images showed that the CuONPs were spherical, with an average size of 50-100 nm. The scanning electron microscopy (SEM)-energy dispersive spectroscopy (EDS) peak was observed approximately at 1 and 8 keV. The X-ray diffraction (XRD) studies indicated that the particles were crystalline in nature. CuONPs effectively inhibited the growth of phytopathogens Ralstonia solanacearum and Xanthomonas axonopodis. The cytotoxic effect of the synthesized CuONPs was analyzed using rat splenocytes. The cell viability was decreased to 94% at 300 μg/mL. |
| Databáze: | OpenAIRE |
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