The control of feather pecking by serotonin
| Autor: | Jaap M. Koolhaas, Y.M. van Hierden, S.M. Korte, S.F. de Boer |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2004 |
| Předmět: |
Dopamine
Piperazines dopaminergic-neurons Developmental psychology Random Allocation Behavioral Neuroscience chemistry.chemical_compound Neurotransmitter Feather pecking Behavior Animal manual restraint Brain Hydroxyindoleacetic Acid Aggression obsessive-compulsive disorder modulation Autoreceptor behavior and behavior mechanisms Psychology psychological phenomena and processes Restraint Physical Serotonin medicine.medical_specialty animal structures mice Neurotransmission Serotonergic behavioral disciplines and activities (5-ht)(1a) receptors Internal medicine medicine Animals Brain Chemistry Dose-Response Relationship Drug laying hens turnover Homovanillic Acid Feathers Serotonin 5-HT1 Receptor Agonists Psychophysiologic Disorders Disease Models Animal Stereotypy (non-human) Endocrinology 5-ht1a autoreceptors chemistry Forebrain 3 4-Dihydroxyphenylacetic Acid s 15535 Chickens ID - Dier en Omgeving |
| Zdroj: | Behavioral Neuroscience, 118/3(3), 575-583 Behavioral Neuroscience 118 (2004) 3 Behavioral Neuroscience, 118(3), 575-583 |
| ISSN: | 0735-7044 |
| Popis: | Feather-pecking behavior in laying hens (Gallus gallus) may be considered a behavioral pathology, comparable to human psychopathological disorders. Scientific knowledge on the causation of such disorders strongly suggests involvement of the serotonergic (5-hydroxytryptamine; 5-HT) system in feather pecking. Previously, chicks from a high-feather-pecking (HFP) line were found to display lower 5-HT turnover levels than chicks from a low-feather-pecking (LFP) line (in response to acute stress; Y. M. van Hierden et al., 2002). The present study investigated whether low 5-HT neurotransmission modulates feather pecking. First, S-15535, a somatodendritic 5-HT1A autoreceptor agonist, was demonstrated to be an excellent tool for reducing 5-HT turnover in the forebrain of LFP and HFP chicks. Second, the most effective dose of S-15535 (4.0 mg/kg body weight) significantly increased severe feather-pecking behavior. The results confirmed the postulation that the performance of feather pecking is triggered by low 5-HT neurotransmission. |
| Databáze: | OpenAIRE |
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