Catfish somatostatin is unique to piscine tissues
| Autor: | Gordon C. Weir, D F Trent, Donald J. Fletcher |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
endocrine system
medicine.medical_specialty animal structures Physiology Clinical Biochemistry Radioimmunoassay Peptide Biology Biochemistry Islets of Langerhans Cellular and Molecular Neuroscience Endocrinology Internal medicine medicine Animals Differential expression Antiserum chemistry.chemical_classification geography geography.geographical_feature_category Pancreatic tissue fungi Fishes Islet Molecular biology Somatostatin chemistry hormones hormone substitutes and hormone antagonists Catfish |
| Zdroj: | Regulatory Peptides. 5:181-187 |
| ISSN: | 0167-0115 |
| DOI: | 10.1016/0167-0115(83)90125-8 |
| Popis: | It has been previously shown that catfish islets contain two distinct forms of somatostatin: somatostatin-14 and the predominant form, catfish somatostatin, which is a 22-residue peptide structurally related to somatostatin-14. Using antisera against this catfish somatostatin and somatostatin-14, other tissues of the catfish and pancreatic tissue of various animals were examined for the presence of these two peptides. Catfish intestine also contained large amounts of catfish somatostatin in comparison to that of somatostatin-14, but the predominant form in catfish brain tissues was somatostatin-14. Relatively small quantities of catfish somatostatin were found in extracts of anglerfish islet, but none were detected in pancreatic tissues of frog, chicken, or rat. Somatostatin-14 was found in relatively large amounts in these other pancreata. These results suggest that catfish somatostatin is found only in piscine tissues and that there may be a differential expression of the two somatostatin genes in those tissues. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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