Difficulty in improving malnutrition and low-grade inflammation in diabetic patients on peritoneal dialysis
| Autor: | Jong-Yeon Kim, Yong-Lim Kim, Chan-Duck Kim, Sun Hee Park, Jung-Ju Seo, Ho-Sang Bae, Sung-Won Park |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors medicine.medical_treatment Renal function Nutritional Status urologic and male genital diseases Kidney Function Tests Gastroenterology Peritoneal dialysis Young Adult Peritoneal Dialysis Continuous Ambulatory Diabetes mellitus Internal medicine medicine Humans Diabetic Nephropathies Renal replacement therapy Prospective Studies Young adult Prospective cohort study Aged Aged 80 and over Inflammation business.industry Continuous ambulatory peritoneal dialysis Malnutrition Hematology Middle Aged medicine.disease Surgery Nephrology Creatinine Kidney Failure Chronic Female Peritoneum business Follow-Up Studies |
| Zdroj: | Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy. 12(6) |
| ISSN: | 1744-9987 |
| Popis: | Continuous ambulatory peritoneal dialysis (CAPD) is commonly used for renal replacement therapy in diabetes mellitus (DM) patients. We investigated the changes of peritoneal transport characteristics, nutritional status, and adequacy and inflammation parameters in diabetic CAPD patients (N = 17) compared to non-diabetic patients (N = 23). Peritoneal equilibrium testing, nutritional, biochemical, and anthropometric parameters and adequacy were prospectively assessed at 1 (baseline), 6 and 12 months after initiating CAPD. The levels of several nutritional parameters were lower and did not change in DM patients over time (P < 0.05) and significantly improved in the non-DM patients over time (P < 0.05). Total weekly creatinine clearance and residual renal function exhibited a rapid decline (P < 0.05) and inflammation parameter levels were higher in DM patients (P < 0.05). Our results showed the difficulty in improvement of nutritional status and inflammatory parameters in diabetic patients during at least the first year of CAPD compared to non-DM patients. |
| Databáze: | OpenAIRE |
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