Morphological effects of whole‐body vibration on remobilization of the tibialis anterior muscle of Wistar rats
| Autor: | Juliana Roncini Gomes da Costa, Gladson Ricardo Flor Bertolini, Ana Tereza Bittencourt Guimarães, Rose Meire Costa, Maria Luiza Serradourada Wutzke, Matheus Felipe Zazula, Lucinéia de Fátima Chasko Ribeiro |
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| Rok vydání: | 2020 |
| Předmět: |
Male
0301 basic medicine Muscle tissue medicine.medical_specialty Histology Physical exercise Protein degradation Vibration Immobilization 03 medical and health sciences 0302 clinical medicine Atrophy Tibialis anterior muscle Internal medicine medicine Animals Whole body vibration Myocyte Rats Wistar Muscle Skeletal Ecology Evolution Behavior and Systematics Electromyography Chemistry Recovery of Function medicine.disease Muscle atrophy Rats Muscular Atrophy 030104 developmental biology Endocrinology medicine.anatomical_structure Anatomy medicine.symptom 030217 neurology & neurosurgery Biotechnology |
| Zdroj: | The Anatomical Record. 303:2857-2864 |
| ISSN: | 1932-8494 1932-8486 |
| Popis: | Therapeutic immobilization is a common treatment for the locomotor system; however, it causes loss of muscle due to disuse, leading to protein degradation and generating atrophy of muscle cells, ultimately changing functionality. In this sense, it is important for remobilization to be initiated early and performed with appropriate therapeutic strategies that enable tissue and functional recovery. One method of remobilization is physical exercise, among which whole body vibration (WBV) has been highlighted and mainly applied in people with reduced mobility. However, there are gaps on the morphological effects WBV has on muscle tissue, so in this study we analyzed the histomorphometry of the tibialis anterior muscle (TA) of Wistar rats remobilized using WBV. For the experiment, 32 male Wistar rats were used and divided into four groups (n = 8/group). Groups consisted of: control (CG), immobilized (IG), immobilized and remobilized freely (FG), and immobilized and remobilized with WBV (WG). After the experimental period, the TA was collected and processed for analysis in light microscopy. When compared to the control group, significant morphological changes were observed, which characterize muscle atrophy and reduction of all histomorphometric parameters of the TA of the immobilized animals. Remobilized animals showed improvement in all parameters, and the WBV was not different from the free remobilization, except for the reduction of central nuclei, which can be related to acceleration of the process of tissue regeneration. Thus, we can conclude that the WBV can have an impact on the acceleration of the muscle regenerative process, and may be beneficial in people with reduced mobility. |
| Databáze: | OpenAIRE |
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