Enteroaggregative Escherichia coli strains secrete a heat-labile toxin antigenically related to E. coli hemolysin
Autor: | H A Hernandez, L Sellers, T J Baldwin, A Aitken, Peter H. Williams, S Knutton |
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Rok vydání: | 1992 |
Předmět: |
Diarrhea
Antigenicity Bacterial Toxins Immunology Enterotoxin Biology medicine.disease_cause Hemolysin Proteins Microbiology Enterotoxins Escherichia coli medicine Humans Phosphorylation Antigens Bacterial Toxin Escherichia coli Proteins Proteins Hemolysin biology.organism_classification Enterobacteriaceae Infectious Diseases Enteroaggregative Escherichia coli Calcium Parasitology Research Article |
Zdroj: | Infection and Immunity. 60:2092-2095 |
ISSN: | 1098-5522 0019-9567 |
Popis: | A protein toxin of approximately 120,000 Da secreted by nonhemolytic enteroaggregative Escherichia coli strains cross-reacted in Western blots (immunoblots) with antibodies raised against the C-terminal region of E. coli hemolysin. Treatment of HEp-2 cells with enteroaggregative E. coli or culture supernatants caused elevation of intracellular calcium and stimulated calcium-dependent protein phosphorylation. |
Databáze: | OpenAIRE |
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