Incidence of Staphylococcus aureus Infections After Elective Surgeries in US Hospitals
| Autor: | Jill Dreyfus, Holly Yu, Julie Gayle, Elizabeth Begier, Margaret A. Olsen |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Microbiology (medical) Staphylococcus aureus medicine.medical_specialty 030501 epidemiology medicine.disease_cause 03 medical and health sciences Inpatient elective 0302 clinical medicine Epidemiology Humans Surgical Wound Infection Medicine Infection control 030212 general & internal medicine Elective surgery Retrospective Studies business.industry Incidence Incidence (epidemiology) Retrospective cohort study Staphylococcal Infections Hospitals Infectious Diseases Emergency medicine Staphylococcus aureus infections 0305 other medical science business |
| Zdroj: | Clinical Infectious Diseases. 73:e2635-e2646 |
| ISSN: | 1537-6591 1058-4838 |
| Popis: | Background Although Staphylococcus aureus is a leading cause of postsurgical infections, national estimates of these infections after elective surgeries based on microbiology data are limited. This study assessed cumulative 180-day postsurgical S. aureus incidence in real-world hospital settings. Methods A retrospective study of adults (≥18 years) undergoing inpatient or hospital-based outpatient elective surgeries from 1/7/2010–30/6/2015 at hospitals (N = 181) reporting microbiology results in the Premier Healthcare Database (PHD). 86 surgical categories were identified from the National Healthcare Safety Network procedures. We classified positive S. aureus cultures using a hierarchy (bloodstream [BSI], surgical site [SSI], and all other types [urinary tract, respiratory, other/unknown site]) and calculated incidence (number of infections divided by the number of elective surgery discharges). We estimated national infection case volumes by multiplying incidence by national inpatient elective surgical discharge estimates using the entire PHD and weights based on hospital characteristics. Results Following 884 803 inpatient elective surgical discharges, 180-day S. aureus infection incidence was 1.35% (0.30% BSI, 0.74% SSI no BSI, 0.32% all other types only). Among 1 116 994 hospital-based outpatient elective surgical discharges, 180-day S. aureus incidence was 1.19% (0.25% BSI, 0.75% SSI no BSI, 0.19% all other types only). Methicillin resistance was observed in ~45% of the S. aureus infections. We estimated 55 764 S. aureus postsurgical infections occurred annually in the US following 4.2 million elective inpatient surgical discharges. Conclusions The high burden of S. aureus infections after both inpatient and outpatient elective surgeries highlights the continued need for surveillance and novel infection prevention efforts. |
| Databáze: | OpenAIRE |
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