Continuous positive airway pressure can improve depression in patients with obstructive sleep apnoea syndrome: a meta-analysis based on randomized controlled trials
| Autor: | Chun-wei Yang, Xiangli Yang, Lin Niu, Fucun Song, Jun Yang, Lin Wang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
China
medicine.medical_specialty Medicine (General) Meta-Analysis and Systematic Review medicine.medical_treatment 030204 cardiovascular system & hematology Biochemistry law.invention 03 medical and health sciences 0302 clinical medicine R5-920 systematic review stomatognathic system Randomized controlled trial law Internal medicine medicine Humans In patient Continuous positive airway pressure Depression (differential diagnoses) Obstructive sleep apnoea syndrome Randomized Controlled Trials as Topic Sleep Apnea Obstructive Continuous Positive Airway Pressure Depression business.industry Biochemistry (medical) Cell Biology General Medicine obstructive sleep apnoea syndrome nervous system diseases respiratory tract diseases meta-analysis Treatment Outcome 030220 oncology & carcinogenesis Meta-analysis business randomised controlled trial Publication Bias |
| Zdroj: | Journal of International Medical Research, Vol 48 (2020) The Journal of International Medical Research |
| ISSN: | 1473-2300 |
| Popis: | Objective Substantial research indicates a clear relationship between obstructive sleep apnoea syndrome (OSAS) and depression. The study aim was to quantitatively evaluate whether continuous positive airway pressure (CPAP) therapy improves mood symptoms in OSAS patients. Methods PubMed and Embase databases were systematically searched up to 2017 for publications on the impact of CPAP on mood symptoms in OSAS patients. Results For the final analysis, nine randomized controlled trials comprising 1,052 patients were selected. The pooled standard mean difference (SMD) of the effect of CPAP on depression was 0.31 (95% confidence interval 0.18, 0.43). A subgroup analysis showed that when CPAP use was greater than 4 hours per night, it tended to be effective in improving patients’ mood symptoms (SMD = 0.38; confidence interval 0.23, 0.54). Analysis of publication bias using Egger’s test found no evidence of publication bias. Conclusion CPAP treatment can improve depression in OSAS patients. |
| Databáze: | OpenAIRE |
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