Site-Specific Clinical Evaluation of the Luminex xTAG Gastrointestinal Pathogen Panel for Detection of Infectious Gastroenteritis in Fecal Specimens
| Autor: | Sanjib Bhattacharyya, Anami Patel, Jose Navidad |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Microbiology (medical) medicine.medical_specialty Time Factors Adolescent Sensitivity and Specificity Gastroenterology In vitro diagnostic Feces Internal medicine parasitic diseases medicine Stool culture Humans Molecular diagnostic techniques Child Pathogen Bacteria business.industry Infant Newborn Clinical performance Infant Reproducibility of Results Bacteriology Gastroenteritis Molecular Diagnostic Techniques Child Preschool Viruses Immunology Female business Clinical evaluation Infectious gastroenteritis |
| Zdroj: | Journal of Clinical Microbiology. 52:3068-3071 |
| ISSN: | 1098-660X 0095-1137 |
| Popis: | We evaluate the clinical performance of the Luminex xTAG gastrointestinal (GI) pathogen in vitro diagnostic (IVD) assay in a comparison between clinical and public health laboratories. The site reproducibility study showed 98.7% sensitivity with high positive and negative agreement values (96.2% and 99.8%, respectively), while assay performance against confirmatory methods resulted in 96.4% sensitivity with similar positive and negative agreement values (90.1% and 99.5%, respectively). High-throughput detection of multiple GI pathogens improved turnaround time, consolidated laboratory workflow, and simplified stool culture practices, thus reducing the overall cost and number of specimens processed. |
| Databáze: | OpenAIRE |
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