Preoperative ketorolac administration has no preemptive analgesic effect for minor orthopaedic surgery
| Autor: | Frederic Camu, M. H. Lauwers, C. Vanlersberghe |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Visual analogue scale Premedication medicine.medical_treatment Analgesic Placebo Double-Blind Method medicine Humans Tolmetin Musculoskeletal System Pain Measurement Pain Postoperative Chemotherapy Morphine business.industry General Medicine Analgesics Non-Narcotic Middle Aged Surgery Analgesics Opioid body regions Ketorolac Anesthesiology and Pain Medicine Opioid Anesthesia Orthopedic surgery Female Minor Surgical Procedures business medicine.drug |
| Zdroj: | Acta Anaesthesiologica Scandinavica. 40:948-952 |
| ISSN: | 1399-6576 0001-5172 |
| DOI: | 10.1111/j.1399-6576.1996.tb04565.x |
| Popis: | The utility of preoperative ketorolac administration to reduce the intensity and duration of postoperative pain was compared with placebo in a randomized double-blind design of 60 ASA 1-2 patients scheduled for minor orthopaedic surgery. No opioids nor local anaesthetic blocks were used during surgery. The patients received either 30 mg ketorolac IV before surgery followed by a placebo injection after surgery or the reverse. Postoperative pain intensity was assessed repeatedly for 6 h using a visual analogue scale. No differences in pain intensity were observed between the two groups except for the initial 15-min postoperative assessments in the ketorolac group. The time to first rescue morphine administration and the total morphine consumption during the 6-h observation period were similar. It is concluded that the preoperative administration of ketorolac did not provide a significant preemptive analgesic benefit with regard to postoperative pain relief and opioid dose-sparing effect. |
| Databáze: | OpenAIRE |
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