| Autor: |
Yvonne Teske, Marian Newton, John Z. Cavendish, Mary Ann F Kirkpatrick, Rhonda McGee, Danielle Przychodzin, Wendell Combest |
| Rok vydání: |
2006 |
| Předmět: |
|
| Zdroj: |
Neuropsychiatric Disease and Treatment |
| ISSN: |
1176-6328 |
| DOI: |
10.2147/nedt.2006.2.4.565 |
| Popis: |
Purpose: This exploratory study examined the relationship between performance on the University of Pennsylvania Smell Identification Test (UPSIT) and the Addenbrooke’s Cognitive Examination (ACE) to identify a possible association between olfaction and mild cognitive impairment(MCI). Design and Methods: 54 community-dwelling older (ages 49–91) volunteers were given the UPSIT and ACE. Results: The ACE identified 7 subjects (13%) who had probable MCI. UPSIT total scores were significantly related to ACE total scores (r = 0.37, p = 0.005). Four specific odorants (mint, lime, chocolate, and cheddar cheese) from the UPSIT identified 4 of the 7 (57.1%) probable MCI subjects. The prevalence rate of MCI in subjects over 65 was 19.4%. Implications: Selective odorants in UPSIT used with ACE show promise as a non-invasive method of detecting MCI in community dwelling elders. Detection of MCI could facilitate earlier interventions and treatment of dementia. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
