Clinical Effects of a Commercial Supplement of Ophiocordyceps sinensis and Ganoderma lucidum on Cognitive Function of Healthy Young Volunteers
| Autor: | Gilit Steiner, Arie Rotstein, Rafi Carasso, Yael Netz, Aviva Zeev, Yarden Har Lev, Tzvi Dwolatski, Sharon Tsuk |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male 0106 biological sciences 0301 basic medicine Ophiocordyceps sinensis Traditional Chinese medicine Placebo 01 natural sciences Applied Microbiology and Biotechnology law.invention 03 medical and health sciences Cognition Randomized controlled trial law 010608 biotechnology Drug Discovery Humans Medicine Single-Blind Method Medicine Chinese Traditional Ganoderma lucidum Pharmacology Cordyceps Traditional medicine biology business.industry Cognitive score biology.organism_classification 030104 developmental biology Dietary Supplements Female business |
| Zdroj: | International Journal of Medicinal Mushrooms. 19:667-673 |
| ISSN: | 1521-9437 |
| DOI: | 10.1615/intjmedmushrooms.2017021202 |
| Popis: | Ophiocordyceps sinensis (= Cordyceps sinensis) and Ganoderma lucidum are medicinal mushrooms used in traditional Chinese medicine. The effects of O. sinensis and G. lucidum on cognitive function have been evaluated through the use of animal models and in vitro studies, which indicated beneficial effects. The purpose of this study was to evaluate the effects of treatment with a commercially available supplement of O. sinensis and G. lucidum on cognitive function in young, healthy human participants. Physical education students (n = 96 [53 men, 43 women]; mean ± standard deviation age, 26.3 ± 3.21 years) were randomly divided into 3 treatment groups: highdose supplement (HD) group, low-dose supplement (LD) group, and a placebo (PL) group. Each group received the treatment, administered by a technician blinded to supplements/placebo, for 30 days. Participants were evaluated for various cognitive functions before and immediately after treatment. Evaluation of cognitive function domains-global cognitive score, memory, executive function, attention, information processing speed, visuospatial ability, verbal function, and motor skills-showed no significant differences between groups. These results indicate that a combination of O. sinensis and G. lucidum supplements for 30 days did not enhance cognitive function domains in young healthy participants. |
| Databáze: | OpenAIRE |
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