New Estimates of Herpes Simplex Virus Type 2 Seroprevalence in England
| Autor: | Jeanne M. Pimenta, Marianne C. Morris-Cunnington, David Brown, Elizabeth L. Miller, NJ Robinson |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
Male Microbiology (medical) Sexually transmitted disease medicine.medical_specialty Adolescent Herpesvirus 2 Human Population Dermatology Serology Age Distribution Seroepidemiologic Studies Health care Epidemiology Humans Medicine Seroprevalence education education.field_of_study business.industry Public health Age Factors Public Health Environmental and Occupational Health Herpes Simplex Middle Aged Virology Confidence interval Infectious Diseases England Female Laboratories business Demography |
| Zdroj: | Sexually Transmitted Diseases. 31:243-246 |
| ISSN: | 0148-5717 |
| DOI: | 10.1097/01.olq.0000118081.54177.95 |
| Popis: | Objectives: There have been few recent population-based herpes simplex virus type 2 (HSV-2) seroprevalence studies in England, but reports from the United States have indicated a 30% rise in HSV-2 seroprevalence between 1976 and 1994. This study aimed to ascertain trends in HSV-2 infection in England between 1991 and 2000. Study Design: Anonymized serum residues collected through public health laboratories across England from individuals aged 16 to 64 years seeking health care through the National Health Service in 1991 (n = 2259) and 2000 (n = 3646) were tested for anti-HSV-2 IgG using the HerpeSelect 2 enzyme-linked immunosorbent assay IgG (Focus). Results: In 9 sites across England, the age- and sex-standardized HSV-2 seroprevalence was 9.7% (95% confidence interval, 8.4-11.0%). Data from 4 sites common to both study years indicated no change in HSV-2 seroprevalence between 1991 and 2000. Conclusions: After adjustment for age, sex, and geographic location, there was no evidence of a change in seroprevalence between 1991 and 2000. |
| Databáze: | OpenAIRE |
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