New Alcamide and Anti-oxidant Activity of Pilosocereus gounellei A. Weber ex K. Schum. Bly. ex Rowl. (Cactaceae)
| Autor: | Nathalia S M Ramos, Marianne G. Fernandes, Girliane Regina da Silva, Temilce Simões de Assis, Pedro Dantas Fernandes, Severino Goncalves de Brito Filho, Jéssica Karina da Silva Maciel, Yanna Carolina Ferreira Teles, Maria de Fátima Vanderlei de Souza, Otemberg Souza Chaves, Tania M. S. Silva, Leonardo P. Felix, Alberício Pereira de Andrade |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Cactaceae
Coumaric Acids Pilosocereus gounellei 7′-ethoxy-trans-feruloyltyramine anti-oxidant activity Pharmaceutical Science Tyramine High-performance liquid chromatography Antioxidants Article Analytical Chemistry lcsh:QD241-441 chemistry.chemical_compound Column chromatography lcsh:Organic chemistry Phenols Drug Discovery Botany Physical and Theoretical Chemistry Chromatography High Pressure Liquid Flavonoids Stigmasterol Traditional medicine Molecular Structure Plant Extracts Organic Chemistry chemistry Phytochemical Chemistry (miscellaneous) Molecular Medicine Medicine Traditional Kaempferol Quercetin |
| Zdroj: | Molecules Molecules; Volume 21; Issue 1; Pages: 11 Molecules, Vol 21, Iss 1, p 11 (2015) |
| ISSN: | 1420-3049 |
| Popis: | The Cactaceae family is composed by 124 genera and about 1438 species. Pilosocereus gounellei, popularly known in Brazil as xique-xique, is used in folk medicine to treat prostate inflammation, gastrointestinal and urinary diseases. The pioneering phytochemical study of P. gounellei was performed using column chromatography and HPLC, resulting in the isolation of 10 substances: pinostrobin (1), β-sitosterol (2), a mixture of sitosterol 3-O-β-d-glucopyranoside/stigmasterol 3-O-β-d-glucopyranoside (3a/3b), 132-hydroxyphaeophytin a (4), phaeophytin a (5), a mixture of β-sitosterol and stigmasterol (6a/6b), kaempferol (7), quercetin (8), 7′-ethoxy-trans-feruloyltyramine (mariannein, 9) and trans-feruloyl tyramine (10). Compound 9 is reported for the first time in the literature. The structural characterization of the compounds was performed by analyses of 1-D and 2-D NMR data. In addition, a phenolic and flavonol total content assay was carried out, and the anti-oxidant potential of P. gounellei was demonstrated. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|