Improvement in botanical standardization of commercial freeze-dried herbal extracts by using the combination of antioxidant capacity and constituent marker concentrations
| Autor: | Luisa Mattoli, Anna Maidecchi, Paolino Ninfali, Francesca Cangi, Lorenzo Gennari, Enrica Biagiotti |
|---|---|
| Předmět: |
food.ingredient
Antioxidant Oxygen radical absorbance capacity Stereochemistry medicine.medical_treatment Antioxidants Analytical Chemistry chemistry.chemical_compound Freeze-drying food Botanical extracts Phenols medicine Environmental Chemistry Food science Medicinal plants Marker compound Chromatography High Pressure Liquid Pharmacology Total phenols biology Plant Extracts biology.organism_classification Standardization Antioxidant capacity Freeze Drying chemistry Olea Herb Trolox Agronomy and Crop Science Food Science |
| Zdroj: | Scopus-Elsevier Europe PubMed Central |
| Popis: | Botanical extracts are standardized to 1 marker compounds (MCs). This standardization provides a certain level of quality control, but not complete quality assurance. Thus, industries are looking for other satisfactory systems to improve standardization. This study focuses on the standardization of herbal medicines by combining 2 parameters: the concentration of the MC and antioxidant capacity. Antioxidant capacity was determined with the oxygen radical absorbance capacity (ORAC) method and the concentrations of the MCs, by high-performance liquid chromatography. Total phenols were also determined by the Folin-Ciocolteau method. The ORAC values, expressed as mol Trolox equivalents/100 g (ORAC ), of 12 commercial herbal extracts were related to the ORAC values of the respective pure MCs at the concentrations at which the MCs occur in products (ORAC-MC ). The ORAC values of 11 extracts were higher than those of the respective MCs and the ratios ORAC-MC /ORAC ranged from 0.007 to 0.7, whereas in the case of Olea europaea leaves, the same ratio was 1.36. The ORAC parameters and their ratios, as well as the linear relationship between ORAC-MC and ORAC , are described and discussed as tools for improving the standardization of herbal products and detecting modifications due to herb processing and storage. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|