Rare Occurrence of Incidental Finding of Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclear Features in Hürthle Cell Adenoma
| Autor: | Biserka Pigac, Silvija Mašić, Zdenka Hutinec, Valentina Mašić |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Adult Pathology medicine.medical_specialty Adenoma endocrine system diseases Noninvasive follicular thyroid neoplasm with papillary-like nuclear features papillary cell carcinoma Thyroid Gland Hurthle cell adenoma Thyroid Thyroid Lobectomy Case Report medicine.disease_cause Scintigraphy thyroid Thyroid carcinoma 03 medical and health sciences 0302 clinical medicine Rare Diseases medicine Adenoma Oxyphilic Humans Hürthle cell adenoma Thyroid neoplasm Frozen section procedure Incidental Findings Neck Pain medicine.diagnostic_test business.industry NIFTP General Medicine medicine.disease 030104 developmental biology medicine.anatomical_structure Treatment Outcome Thyroid Cancer Papillary 030220 oncology & carcinogenesis Thyroidectomy Female business |
| Zdroj: | Medical Archives |
| ISSN: | 1986-5961 |
| Popis: | INTRODUCTION: Hürthle cell adenoma is a rare benign lesion of the thyroid gland, however, controversies about its potential malignant behavior still remain. Among thyroid neoplasms, papillary carcinoma is the most common variant with great variety of histological subtypes demonstrating different biological behavior. AIM: To raise the awareness of possible coexistence of these two lesions and discussion about possible therapeutic approaches. CASE REPORT: A 42 year old female patient was examined because of the pain in the thyroid area. Cytological examination suggested Hürthle cell adenoma. Subsequently, right thyroid lobectomy was performed. Intraoperative frozen sections confirmed the diagnosis, yet final histological analysis revealed encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC), now reclassified as noninvasive follicular thyroid neoplasm with papillary- like nuclear features (NIFTP) within the adenoma, which was not noticed through scintigraphy, ultrasound, cytological and frozen section analysis. CONCLUSIONS: Problems concerning both diagnostic and therapeutic approach to these lesions are being discussed, since opinions reported in the literature are divided, posing great challenge for the clinician in determining adequate therapeutic procedures. To raise the awareness of possible coexistence of these two lesions and discussion about possible therapeutic approaches. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|