Ayahuasca: Uses, Phytochemical and Biological Activities
| Autor: | Francisco Javier Alarcón-Aguilar, Edgar Antonio Estrella-Parra, Julio César Almanza-Pérez |
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| Rok vydání: | 2019 |
| Předmět: |
Psychotria viridis – dimethyltryptamine
Psychotria viridis β-carbolines Psychoactive substance Review Plant Science Toxicology 01 natural sciences Biochemistry Analytical Chemistry lcsh:Botany Banisteriopsis caapi Creative thinking Beneficial effects Pharmacology Traditional medicine biology 010405 organic chemistry Amazon rainforest Organic Chemistry Ayahuasca biology.organism_classification lcsh:QK1-989 0104 chemical sciences Psychotherapy 010404 medicinal & biomolecular chemistry Psychology Food Science Amazon basin |
| Zdroj: | Natural Products and Bioprospecting Natural Products and Bioprospecting, Vol 9, Iss 4, Pp 251-265 (2019) |
| ISSN: | 2192-2209 2192-2195 |
| Popis: | Ayahuasca (caapi, yajé), is a psychoactive brew from the Amazon Basin region of South America traditionally considered a “master plant.” It is prepared as a decoction from Banisteriopsis caapi and Psychotria viridis, which it is thought that it stimulates creative thinking and visual creativity. Native healers of the Orinoco and Amazon basins have used traditionally ayahuasca as a healing tool for multiple purposes, particularly to treat psychological disorders in the patients, with some beneficial effects experimentally and clinically validated. Recently, several syncretic religions, as the “União de Vegetal” (UDV) group in Brazil, have been spread around the world. The use of ayahuasca has been popularized by internet and smart-shops, bringing the psychoactive substance to new highs, emerging new “ayahuasqueros.” Ayahuasca has alkaloids as β-carbolines and dimethyltryptamines, which inhibit the monoamine oxidase and active the 5-HT2A (5-hydroxytryptamine) receptor, respectively, resulting in hallucinations in the users. Ayahuasca induces a psychedelic change in the anteroposterior coupling of the electrophysiological brain oscillations in humans. Traditional ayahuasca beverage is generating pharmacological, commercial and spiritual interest among the scientific community, government people, and different populations worldwide. The goal of this article is to report about the uses, chemistry and biological activities of ayahuasca. Graphical Abstract |
| Databáze: | OpenAIRE |
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