| Autor: |
Lei Wang, Xue-qing Tang, Yang Shi, Hui-min Li, Zi-yu Meng, Hui Chen, Xiao-han Li, Yong-chao Chen, Heng Liu, Yang Hong, Heng-hui Xu, Ling Liu, Limin Zhao, Wei-na Han, Xin Liu, Yong Zhang |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Acta pharmacologica Sinica. |
| ISSN: |
1745-7254 |
| Popis: |
Heart aging is characterized by left ventricular hypertrophy and diastolic dysfunction, which in turn induces a variety of cardiovascular diseases. There is still no therapeutic drug to ameliorate cardiac abnormities in heart aging. In this study we investigated the protective effects of berberine (BBR) and its derivative tetrahydroberberrubine (THBru) against heart aging process. Heart aging was induced in mice by injection of D-galactose (D-gal, 120 mg · kg |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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