The Legacy of Recurrent Introgression during the Radiation of Hares

Autor: José Melo-Ferreira, Franz Suchentrunk, L. Scott Mills, Paulo C. Alves, Mafalda S. Ferreira, Colin M. Callahan, Pierre Boursot, Jeffrey M. Good, Matthew R. Jones, Liliana Farelo, Zelalem Tolesa
Přispěvatelé: Universidade do Porto, University of Montana, Hawassa University, Institut des Sciences de l'Evolution de Montpellier (UMR ISEM), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre National de la Recherche Scientifique (CNRS)-Institut de recherche pour le développement [IRD] : UR226, North Carolina State University [Raleigh] (NC State), University of North Carolina System (UNC), Faculdade de Ciências, Universidade do Porto = University of Porto, Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Institut de recherche pour le développement [IRD] : UR226-Centre National de la Recherche Scientifique (CNRS)
Rok vydání: 2020
Předmět:
Zdroj: Systematic Biology
Systematic Biology, Oxford University Press (OUP), 2020, 70, pp.593-607. ⟨10.1093/sysbio/syaa088⟩
Systematic Biology, 2020, 70, pp.593-607. ⟨10.1093/sysbio/syaa088⟩
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
ISSN: 1076-836X
1063-5157
DOI: 10.1093/sysbio/syaa088⟩
Popis: Hybridization may often be an important source of adaptive variation, but the extent and long-term impacts of introgression have seldom been evaluated in the phylogenetic context of a radiation. Hares (Lepus) represent a widespread mammalian radiation of 32 extant species characterized by striking ecological adaptations and recurrent admixture. To understand the relevance of introgressive hybridization during the diversification ofLepus, we analyzed whole exome sequences (61.7 Mb) from 15 species of hares (1- 4 individuals per species), spanning the global distribution of the genus, and two outgroups. We used a coalescent framework to infer species relationships and divergence times, despite extensive genealogical discordance. We found high levels of allele sharing among species and show that this reflects extensive incomplete lineage sorting and temporally layered hybridization. Our results revealed recurrent introgression at all stages along theLepusradiation, including recent gene flow between extant species since the last glacial maximum, but also pervasive ancient introgression occurring since near the origin of the hare lineages. We show that ancient hybridization between northern hemisphere species has resulted in shared variation of potential adaptive relevance to highly seasonal environments, including genes involved in circadian rhythm regulation, pigmentation, and thermoregulation. Our results illustrate how the genetic legacy of ancestral hybridization may persist across a radiation, leaving a long-lasting signature of shared genetic variation that may contribute to adaptation within and among species.
Databáze: OpenAIRE
Externí odkaz: