Severe or marginal iron deficiency affects spontaneous physical activity in rats
| Autor: | Janet R. Hunt, Carol A Zito, LuAnn K. Johnson, J Erjavec |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Light Iron Physical activity Medicine (miscellaneous) Physical exercise Motor Activity Biology Rats Sprague-Dawley Hemoglobins Random Allocation Light Cycle Internal medicine Male rats medicine Animals Analysis of Variance Dietary iron Nutrition and Dietetics Body Weight Iron Deficiencies Iron deficiency Darkness medicine.disease Circadian Rhythm Diet Rats Endocrinology Hematocrit Regression Analysis Hemoglobin Iron status |
| Zdroj: | The American Journal of Clinical Nutrition. 59:413-418 |
| ISSN: | 0002-9165 |
| DOI: | 10.1093/ajcn/59.2.413 |
| Popis: | The influence of dietary iron on spontaneous activity was investigated in growing rats. Male rats weighing 97 +/- 10 g fed diets containing 4.6 (deficient), 19.9 (marginal), and 108.4 (adequate) mg Fe/kg diet for 8 wks had hemoglobin values of 52 +/- 6, 152 +/- 4, and 159 +/- 6 g/L, and liver nonheme iron concentrations of 0.79 +/- 0.24, 1.36 +/- 0.39, and 4.58 +/- 0.62 mumol/g, respectively. Body weights were affected only at the lowest iron intake. Diurnal activity was not reversed by iron status; all animals were more active during the dark cycle than the light cycle. Iron deficiency resulted in less time and frequency of horizontal, vertical, and stereotypic movements; less distance moved; and less frequent rotations. Movement speed of iron-deficient rats was faster during early iron deficiency. In the light, rats with marginal iron nutriture were generally more active than were iron-deficient or iron-adequate animals. In the dark, activity generally decreased with each reduction in dietary iron. |
| Databáze: | OpenAIRE |
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