Radioimmunoassay for plasma betamethasone 17-benzoate
| Autor: | Henmi Zen-ichi, Mizuchi Akira, Miyachi Yukitaka, Okada Nobuyuki |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
medicine.medical_specialty
Hydrocortisone Clinical Biochemistry Radioimmunoassay Cross Reactions Betamethasone Biochemistry Endocrinology Internal medicine medicine Animals Humans In patient Molecular Biology Dexamethasone Pharmacology Antiserum Chromatography Chemistry Microchemistry Organic Chemistry Occlusive dressing Standard curve Rabbits medicine.drug Conjugate |
| Zdroj: | Steroids. 26:635-645 |
| ISSN: | 0039-128X |
| DOI: | 10.1016/0039-128x(75)90056-2 |
| Popis: | A sensitive radioimmunoassay for plasma betamethasone 17-benzoate has been developed. The antiserum used was obtained by immunizing rabbits with betamethasone 17-benzoate-21-hemisuccinate-bovine-serum-albumin conjugate. All of the endogenous steroids tested cross reacted less than 0.0155. A standard curve was established with a useful range from 0.05–5 ng. Reliability criteria were satisfactory. Measurement of plasma concentrations of betamethasone 17-benzoate was performed in patients and in rabbits following occlusive dressing of betamethasone 17-benzoate cream and gel base. |
| Databáze: | OpenAIRE |
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