Whole‐body imaging of the distribution of mercury released from dental fillings into monkey tissues
| Autor: | Leszek J. Hahn, Reinhard Kloiber, Ronald W. Leininger, Fritz L. Lorscheider, Murray J. Vimy |
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| Rok vydání: | 1990 |
| Předmět: |
Diagnostic Imaging
Male chemistry.chemical_element Dentistry engineering.material Kidney Dental Amalgam Biochemistry stomatognathic system Genetics Animals Tissue Distribution Molecular Biology Dental fillings Tomography Emission-Computed Single-Photon High concentration Mercury Radioisotopes Gastrointestinal tract Dentition Chemistry business.industry Mercury Anatomy Mercury (element) Amalgam (dentistry) Macaca fascicularis stomatognathic diseases Jaw Human mouth engineering business Digestive System Feeding Regimen Biotechnology |
| Zdroj: | The FASEB Journal. 4:3256-3260 |
| ISSN: | 1530-6860 0892-6638 |
| DOI: | 10.1096/fasebj.4.14.2227216 |
| Popis: | The fate of mercury (Hg) released from dental "silver" amalgam tooth fillings into human mouth air is uncertain. A previous report about sheep revealed uptake routes and distribution of amalgam Hg among body tissues. The present investigation demonstrates the bodily distribution of amalgam Hg in a monkey whose dentition, diet, feeding regimen, and chewing pattern closely resemble those of humans. When amalgam fillings, which normally contain 50% Hg, are made with a tracer of radioactive 203Hg and then placed into monkey teeth, the isotope appears in high concentration in various organs and tissues within 4 wk. Whole-body images of the monkey revealed that the highest levels of Hg were located in the kidney, gastrointestinal tract, and jaw. The dental profession's advocacy of silver amalgam as a stable tooth restorative material is not supported by these findings. |
| Databáze: | OpenAIRE |
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