Successful Treatment with Edoxaban for Disseminated Intravascular Coagulation in a Case of Aortic Dissection Complicated with Immune Thrombocytopenic Purpura
| Autor: | Hironori Kobayashi, Nobuhiko Nomoto, Hirohito Sone, Yoshinobu Seki, Yuki Okoshi, Shun Uemura |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Exacerbation Pyridines Case Report direct oral anticoagulant 030204 cardiovascular system & hematology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Edoxaban hemic and lymphatic diseases Atrial Fibrillation Internal Medicine medicine Humans Platelet Aged Disseminated intravascular coagulation Aortic dissection Purpura Thrombocytopenic Idiopathic Platelet Count business.industry Anticoagulants Atrial fibrillation General Medicine Disseminated Intravascular Coagulation medicine.disease Thrombocytopenic purpura Surgery Aortic Dissection Thiazoles chemistry edoxaban Prednisolone Female 030211 gastroenterology & hepatology business circulatory and respiratory physiology medicine.drug |
| Zdroj: | Internal Medicine |
| ISSN: | 1349-7235 0918-2918 |
| Popis: | A 70-year-old woman was hospitalized for exacerbation of chronic idiopathic thrombocytopenic purpura (ITP) and disseminated intravascular coagulation (DIC) from old aortic dissection. Initially, we increased the dose of prednisolone for ITP. However, her bleeding tendency caused by DIC worsened despite the rapid recovery of her platelet count, and the required amount of fresh-frozen plasma for transfusion increased. The administration of edoxaban for atrial fibrillation led to the marked improvement of her DIC status without serious adverse events. This case suggests that a direct oral anticoagulant may be an effective treatment for DIC caused by aortic dissection. |
| Databáze: | OpenAIRE |
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