Frey syndrome treatment with botulinum toxin
| Autor: | Pavel Dulguerov, Pierre Piletta, Didier Quinodoz, Grégoire Cosendai, Willy Lehmann |
|---|---|
| Předmět: |
Botulinum Toxins
Erythema Cholinergic Agents Sweating Gustatory Sweating SWEAT Gustatory/drug therapy Injection site medicine Humans In patient Color measurement ddc:616 integumentary system business.industry medicine.disease Botulinum toxin ddc:616.8 Cholinergic Agents/administration & dosage/therapeutic use Otorhinolaryngology Anesthesia Botulinum Toxins/administration & dosage/therapeutic use Surgery medicine.symptom business Digital surface Infiltration (medical) medicine.drug |
| Zdroj: | Scopus-Elsevier Otolaryngology-Head and Neck Surgery, Vol. 122, No 6 (2000) pp. 821-7 |
| ISSN: | 0194-5998 |
| Popis: | The goal of this work is to present our results of the intradermic infiltration with botulinum toxin in patients with Frey syndrome. Sixteen hemifaces in 15 patients were studied. Gustatory stimulation was evoked by sucking on a slice of lemon while measurements were done on both hemifaces, with the normal side being used as a control. Skin temperature and color (erythema) were measured with a digital surface thermometer and a skin chromameter, respectively. Sweat quantity and surface were measured by using the previously described blotting paper and iodine-sublimated paper histogram methods, respectively. Testing was repeated 2 weeks after skin infiltration with botulinum toxin (dilution of 50 U/mL). The interinjection distances were 1 cm, and 0.1 mL (5 U) was infiltrated at each injection site. Frey syndrome complaints disappeared in all patients. Small residual amounts of sweat were measurable. The difference in sweat quantity before and after botulinum toxin infiltration was significant in every patient (P < 0.001). Skin temperature and color measurement gave inconclusive results. In conclusion, Frey syndrome treatment with botulinum toxin is an efficient and well-tolerated technique. Further work should address the optimal injection parameters. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|