Débridement and Autologous Lipotransfer for Chronic Ulceration of the Diabetic Foot and Lower Limb Improves Wound Healing
| Autor: | Christian Herold, Randy De Baerdemaeker, Tuan Huynh, Julius Hoehne, Tilman Stasch, Siegfried Grandel |
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| Přispěvatelé: | Plastic Surgery |
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Reconstructive surgery medicine.medical_specialty medicine.medical_treatment Diabetic angiopathy Transplantation Autologous surgery Medicine Humans Prospective Studies Prospective cohort study Aged Adipose Tissue/transplantation Aged 80 and over Wound Healing Debridement integumentary system business.industry Vascular disease Leg Ulcer Leg Ulcer/surgery Middle Aged medicine.disease Diabetic foot Diabetic Foot Surgery Transplantation Adipose Tissue Diabetic Foot/surgery Diabetic Angiopathies/surgery Chronic Disease Female business Wound healing Diabetic Angiopathies |
| Zdroj: | Plastic and reconstructive surgery. 136(6) |
| ISSN: | 1529-4242 |
| Popis: | Background The application of autologous lipotransfer (fat grafting, lipofilling) in reconstructive surgery is steadily becoming more popular as evidence of the regenerative and reparative effects of fat becomes better known. The authors investigated the use of autologous lipotransfer for treatment of chronic diabetic and other foot and lower limb ulcers. Methods Twenty-six patients with nonhealing wounds were treated with surgical debridement and autologous lipotransfer (using the debridement and autologous lipotransfer method). The mean age of the wounds before intervention was 16.7 months. Wound size after debridement averaged 5.1 ± 2.6 cm2. On average, 7.1 ± 3.3 cc of lipoaspirate was transferred into the wound area. Results Twenty-two of 25 wounds (88 percent) healed completely within a mean of 68.0 ± 33.0 days. A reduction of wound size by 50 percent was achieved after an average of 4 weeks. In one patient with an ulcer within particularly scarred tissues on the lower limb, a repeated session of lipotransfer led to complete wound healing after another 4 weeks. Conclusion The authors describe a simple and useful technique to improve wound healing in diabetic feet and chronic lower limb ulcers with a background of peripheral vascular disease, where other interventional options to achieve wound healing have failed. |
| Databáze: | OpenAIRE |
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