Flare-up reactions in severe drug hypersensitivity: infection or ongoing T-cell hyperresponsiveness
Autor: | Lukas Emanuel Jörg-Walther, Werner J. Pichler, Alexandra Schüller, Annette Wochner, Karin Helsing, B Schnyder, Arthur Helbling |
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Jazyk: | angličtina |
Rok vydání: | 2015 |
Předmět: |
Drug
medicine.medical_specialty Pathology T cell media_common.quotation_subject Blood count drug rash with eosinophilia and systemic symptoms (DRESS) 610 Medicine & health Case Reports Lymph node swelling Medicine Flare up Confusion media_common flare-up reaction relapse business.industry General Medicine Dermatology infection 3. Good health medicine.anatomical_structure Differential diagnosis medicine.symptom business Drug hypersensitivity |
Zdroj: | Jörg-Walther, Lukas; Schnyder, Benno; Helbling, Arthur; Helsing, Karin; Schüller, Alexandra; Wochner, Annette; Pichler, Werner (2015). Flare-up reactions in severe drug hypersensitivity: infection or ongoing T-cell hyperresponsiveness. Clinical case reports, 3(10), pp. 798-801. Wiley 10.1002/ccr3.346 Clinical Case Reports |
Popis: | Key Clinical Message “Flare-up” reactions are late manifestations of severe T-cell-mediated drug hypersensitivity reactions. Management is anti-inflammatory treatment and avoiding unnecessary medicines. Symptoms like fever, lymph node swelling, and blood count abnormalities may lead to confusion with bacterial infections. For prompt recognition it is important to keep the differential diagnosis in mind. |
Databáze: | OpenAIRE |
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