The Use of the Velocity Selective Recording Technique to Reveal the Excitation Properties of the Ulnar Nerve in Pigs
| Autor: | Taha Al-Muhammadee Janjua, Thomas Gomes Nørgaard dos Santos Nielsen, Benjamin Metcalfe, Felipe Rettore Andreis, Suzan Meijs, Winnie Jensen |
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| Rok vydání: | 2021 |
| Předmět: |
Compound action potential
Swine 0206 medical engineering Action Potentials TP1-1185 02 engineering and technology electroneurography Biochemistry Article Analytical Chemistry compound action potential velocity selective recording multi-electrode cuff neural recording 03 medical and health sciences Nerve Fibers 0302 clinical medicine Animals Electrical and Electronic Engineering Multi-electrode cuff Electrodes Instrumentation Ulnar Nerve Chemical technology 020601 biomedical engineering Velocity selective recording Electric Stimulation Atomic and Molecular Physics and Optics 3. Good health Electroneurography Neural recording 030217 neurology & neurosurgery |
| Zdroj: | Sensors, Vol 22, Iss 58, p 58 (2022) Sensors (Basel, Switzerland) Andreis, F R, Metcalfe, B, Janjua, T A M, Jensen, W, Meijs, S & Nielsen, T G N D S 2022, ' The Use of the Velocity Selective Recording Technique to Reveal the Excitation Properties of the Ulnar Nerve in Pigs ', Sensors, vol. 22, no. 1, 58 . https://doi.org/10.3390/s22010058 Sensors; Volume 22; Issue 1; Pages: 58 |
| ISSN: | 1424-8220 |
| Popis: | Decoding information from the peripheral nervous system via implantable neural interfaces remains a significant challenge, considerably limiting the advancement of neuromodulation and neuroprosthetic devices. The velocity selective recording (VSR) technique has been proposed to improve the classification of neural traffic by combining temporal and spatial information through a multi-electrode cuff (MEC). Therefore, this study investigates the feasibility of using the VSR technique to characterise fibre type based on the electrically evoked compound action potentials (eCAP) propagating along the ulnar nerve of pigs in vivo. A range of electrical stimulation parameters (amplitudes of 50 μA–10 mA and pulse durations of 100 μs, 500 μs, 1000 μs, and 5000 μs) was applied on a cutaneous and a motor branch of the ulnar nerve in nine Danish landrace pigs. Recordings were made with a 14 ring MEC and a delay-and-add algorithm was used to convert the eCAPs into the velocity domain. The results revealed two fibre populations propagating along the cutaneous branch of the ulnar nerve, with mean velocities of 55 m/s and 21 m/s, while only one dominant fibre population was found for the motor branch, with a mean velocity of 63 m/s. Because of its simplicity to provide information on the fibre selectivity and direction of propagation of nerve fibres, VSR can be implemented to advance the performance of the bidirectional control of neural prostheses and bioelectronic medicine applications. |
| Databáze: | OpenAIRE |
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