Metallosis in a Dog as a Long-Term Complication Following Total Hip Arthroplasty
| Autor: | Michael P. Kowaleski, Barry Lai, Samuel H Jennings, Galit H. Frydman, Trisha J. Oura, Mallory J. DiVincenzo, Charles R. Vanderburg |
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| Rok vydání: | 2017 |
| Předmět: |
musculoskeletal diseases
Male Reoperation medicine.medical_specialty Metallic debris Osteolysis 040301 veterinary sciences medicine.medical_treatment Arthroplasty Replacement Hip Laser Capture Microdissection 0403 veterinary science Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Dogs Postoperative Complications medicine Metallosis Animals Titanium 030222 orthopedics General Veterinary business.industry Soft tissue 04 agricultural and veterinary sciences medicine.disease Arthroplasty Surgery Prosthesis Failure Lameness Metals Polyethylene Chromium Alloys Hip Prosthesis business Complication Total hip arthroplasty |
| Zdroj: | Veterinary pathology. 54(5) |
| ISSN: | 1544-2217 |
| Popis: | Metallosis is the accumulation of metallic debris in soft tissues resulting from wear following total joint replacement. A dog was evaluated for lameness 4 years after total hip arthroplasty using a titanium alloy and cobalt chromium total hip system. Radiographs revealed severe acetabular component wear, implant-bone interface deterioration, and peri-acetabular osteolysis. During surgical revision, black periarticular tissue surrounded the implants. Histologically, there was fibrosis and granulomatous inflammation with abundant, intra- and extracellular, black, granular material and smaller amounts of clear punctate to acicular material. Laser capture microdissection followed by x-ray fluorescence microscopy indicated the material contained large amounts of titanium with smaller amounts of vanadium, cobalt, and chromium, confirming the diagnosis of metallosis. The clear material was birefringent under cross-polarized light, stained positive with Oil-Red-O, and thus was consistent with polyethylene. Metallosis exhibits characteristic gross and histologic lesions and is a differential diagnosis for aseptic loosening of hip implants. |
| Databáze: | OpenAIRE |
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