Intradialytic glucose infusion increases polysulphone membrane permeability and post-dilutional haemodiafiltration performances
| Autor: | J Y Bosc, Laurie J. Garred, Fabrice Vaussenat, Martine Leblanc, Hélène Leray-Moragues, Bernard Canaud |
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| Rok vydání: | 2000 |
| Předmět: |
Adult
Male medicine.medical_specialty Membrane permeability Polymers medicine.medical_treatment Ultrafiltration Biocompatible Materials Hemodiafiltration Permeability chemistry.chemical_compound Dialysis Solutions Internal medicine medicine Humans Urea Renal Insufficiency Sulfones Infusions Intravenous Dialysis Transplantation Creatinine business.industry Membranes Artificial Venous blood Glucose Endocrinology chemistry Nephrology Tonicity Female Hemodialysis business |
| Zdroj: | Nephrology Dialysis Transplantation. 15:511-516 |
| ISSN: | 1460-2385 0931-0509 |
| DOI: | 10.1093/ndt/15.4.511 |
| Popis: | INTRODUCTION During real-time monitoring of the ultrafiltration coefficient (Kuf) in haemodiafiltration (HDF), it was noticed that the ultrafiltration performance of polysulphone membrane dialysers increased when hypertonic glucose (D50%) was administered through the venous blood return. METHODS This observation was explored in six non-diabetic chronic dialysis patients during 48 HDF sessions using 1.8 m(2) polysulphone membrane dialysers. In all six patients, 24 sessions were performed with glucose supplementation (as a continuous D50% (500 g/l) infusion at 40 ml/h) and 24 sessions without supplementation. RESULTS Glucose supplementation led to a marked increase in Kuf from 22.8+/-2.2 (without D50%, n=24) to 32. 1+/-3.9 ml/h/mmHg (with D50%, n=24) (P |
| Databáze: | OpenAIRE |
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