Supplementary Methods from MDM2 Small-Molecule Antagonist RG7112 Activates p53 Signaling and Regresses Human Tumors in Preclinical Cancer Models

Autor:	Lyubomir T. Vassilev, Binh Vu, Peter Wovkulich, Frank Podlaski, Michael Linn, Kwong-Him To, Kenneth Kolinsky, Edmund Lee, Rosario Garrido, Christine Tardell, Brian Higgins Mingxuan Xia, Zoran Filipovic, Kathryn Packman, Bradford Graves, Christian Tovar
Rok vydání:	2023
DOI:	10.1158/0008-5472.22398767.v1
Popis:	PDF file - 136K, Includes HTRF, cell growth/viability, apoptosis assays and biacore, crystal structure and animal studies. Also includes supplemental references.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::462335161b3d3a7a48af64749143adb9 https://doi.org/10.1158/0008-5472.22398767.v1 Zobrazit plný text záznamu