Neurogenesis during caudal spinal cord regeneration in adult newts
| Autor: | J. Coulon, Abdellatif Benraiss, Jean-Pierre Arsanto, Y. Thouveny |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Central Nervous System
Tail Cellular differentiation Central nervous system chemistry.chemical_compound Pleurodeles Glial Fibrillary Acidic Protein Genetics medicine Animals Regeneration Cells Cultured Spinal Cord Regeneration Neurons Glial fibrillary acidic protein biology Neurogenesis Cell Differentiation Anatomy Spinal cord Immunohistochemistry Cell biology medicine.anatomical_structure Spinal Cord chemistry Phosphopyruvate Hydratase biology.protein Neuroglia Cell Division Bromodeoxyuridine Developmental Biology |
| Zdroj: | Development Genes and Evolution. 209:363-369 |
| ISSN: | 1432-041X 0949-944X |
| DOI: | 10.1007/s004270050265 |
| Popis: | After tail amputation in urodele amphibians, dramatic changes appear in the spinal cord rostral to the amputation level. Transection induces a proliferation response in cells lining the ependymal canal, giving rise to an ependymal tube in which neurogenesis occurs. Using the thymidine analog bromodeoxyuridine (BrdU) in short- and long-term labeling of cells undergoing DNA synthesis (S phase of the cell cycle), specific cell markers, and cell cultures, we show that neurons derive from the proliferative ependymal layer of the ependymal tube. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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