Acute effects of oxytocin in music performance anxiety: a crossover, randomized, placebo-controlled trial
| Autor: | Flávia de Lima Osório, Marcos Hortes Nisihara Chagas, Alini Daniéli Viana Sabino |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Performance Anxiety media_common.quotation_subject Emotions Placebo-controlled study Oxytocin 03 medical and health sciences 0302 clinical medicine Double-Blind Method medicine Humans Administration Intranasal media_common Pharmacology Cross-Over Studies business.industry Cognition 030227 psychiatry Facial Expression Clinical trial Treatment Outcome Mood Feeling ANÁLISE FACIAL Anxiety Analysis of variance medicine.symptom business Facial Recognition Brazil Music 030217 neurology & neurosurgery Clinical psychology medicine.drug |
| Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| Popis: | Individuals with music performance anxiety (MPA) present physical, behavioral, and cognitive manifestations of anxiety, in addition to information processing deficits, especially in facial emotion recognition (FER).To assess the effects of a single dose of intranasal oxytocin (24 IU) on FER in a sample of musicians with high and low MPA (primary outcome), as well as indicators of mood/anxiety and self-assessed performance (secondary outcomes).Crossover, randomized, double-blind, placebo-controlled trial involving 43 male musicians with different levels of MPA. Participants completed a static facial emotion recognition task and self-rated mood and performance scales. Data were analyzed using ANOVA 2 × 0 for crossover trials and the Omnibus test (measure of separability between intervention and carryover effects).Only musicians with high MPA treated with oxytocin had a higher accuracy in the recognition of happiness (p 0.03; d 0.72). No effects of oxytocin were found on mood indicators or on self-perceived performance, regardless of MPA level.The results indicate possible benefits of the acute treatment with oxytocin in MPA, which may improve the management of this common and disabling condition that affects professional musicians. The appropriate perception of positive feedback may increase confidence and feelings of social acceptance, reducing symptoms associated with the condition. The lack of effects on mood/anxiety and cognition may be explained by the context-dependent characteristic of the effects of oxytocin, since the experiment did not represent an actual situation of social threat.Brazilian Clinical Trials Registry (Registro Brasileiro de Ensaios Clínicos): No. RBR-9cph2q. |
| Databáze: | OpenAIRE |
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