Socio demographic wise risk assessment of thyroid function abnormalities in far western region of Nepal: A hospital based descriptive study
| Autor: | Mukesh Kumar Shrewastwa, C. Thanpari, Naval Kishor Yadav, R. K. Mittal, Brijesh Sathian |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Microbiology (medical)
Thyroid function medicine.medical_specialty endocrine system lcsh:Arctic medicine. Tropical medicine genetic structures endocrine system diseases lcsh:RC955-962 Socio demographics Population Alternative medicine lcsh:Medicine Bioinformatics Nepal medicine education Risk assessment education.field_of_study business.industry lcsh:R Hospital based eye diseases Thyroid disorder Infectious Diseases Family medicine Epidemiology Investigation Descriptive research business hormones hormone substitutes and hormone antagonists |
| Zdroj: | Asian Pacific Journal of Tropical Disease, Vol 3, Iss 2, Pp 150-154 (2013) |
| ISSN: | 2222-1808 |
| Popis: | Objective: To know the status of thyroid disorder in population of far western region of Nepal. Methods: A total of 808 cases (1 33 men and 675 non pregnant women) were included and study was carried out using data retrieved from the register maintained in the Department of Biochemistry of the Nepalgunj Teaching Hospital between 1st January, 2011 and 28th February, 2012. The variables collected were age, sex, and thyroid function profile including free T3, free T4 and TSH. Results: The percentage of thyroid disorders was 33.66% in far western region of Nepal. The people were highly affected by overt hyperthyroidism (14.9%) followed by subclinical hyperthyroidism (9.9%). The subclinical hypothyroidism was 7.9% while 1% overt hypothyroidism only in a far western region of Nepal. Females were highly affected by overt hyperthyroidism (17.8%), followed by subclinical hyperthyroidism (11.9%). A total of 5.9% females were affected by subclinical hypothyroidism while only 1.2% by overt hypothyroidism. Males were affected only by subclinical hypothyroidism (18.0%) in this present study. High number of total thyroid dysfunction was observed in 21 to 40 years of age groups, followed by 41 to 60 years of age groups. Less than 40 years people were having 1.03, 0.99, 2.51 and 1.15 times risk of developing overt hyperthyroidism, subclinical hyperthyroidism, overt hypothyroidism and subclinical hyperthyroidism respectively compared to greater than 40. Female were having 0.29 times risk of developing subclinical hyperthyroidism compared to male. But overt hyperthyroidism, subclinical hyperthyroidism and overt hypothyroidism female were having more risk of developing compared to male. Conclusions: The thyroid disorder, especially overt hyperthyroidism (14.9%) and subclinical hyperthyroidism (9.9%) was high. Further studies are required to characterize the reasons for this high prevalence. |
| Databáze: | OpenAIRE |
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