Root canal treatment of compromised teeth as alternative treatment for patients receiving bisphosphonates: 60-month results of a prospective clinical study
| Autor: | Maria Giovanna Gandolfi, Gian Andrea Pelliccioni, Fausto Zamparini, Andrea Spinelli, Davide B Gissi, Carlo Prati |
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| Přispěvatelé: | Zamparini F., Pelliccioni G.A., Spinelli A., Gissi D.B., Gandolfi M.G., Prati C. |
| Rok vydání: | 2020 |
| Předmět: |
Root canal
medicine.medical_treatment 0206 medical engineering Dentistry 02 engineering and technology MRONJ Crown (dentistry) 03 medical and health sciences 0302 clinical medicine Root Canal Obturation medicine Bisphosphonate Humans Clinical significance Prospective Studies Prospective cohort study General Dentistry Survival rate Survival analysis Aged prospective cohort study Diphosphonates business.industry 030206 dentistry PAI Middle Aged 020601 biomedical engineering Alternative treatment Root Canal Therapy medicine.anatomical_structure Prospective clinical study root canal treatment Dental Pulp Cavity business |
| Zdroj: | International endodontic journalReferences. 54(2) |
| ISSN: | 1365-2591 |
| Popis: | Aim: This 60-month prospective study aimed to evaluate tooth survival and healing rates after root canal treatment in patients taking bisphosphonates (BPs). Secondary outcomes were complications and clinical variables observed during and after treatment. Methods: Root canal treatment was performed using manual K-file canal instrumentation and a carrier-based filling technique with an epoxy resin-based sealer. Teeth without adequate root/crown integrity were restored by trained operators at the tissue level (TL group) to prevent occlusal/mechanical stress and to enable periapical lesion healing without the risk of root fracture. Other teeth were restored with normal occlusal contacts (OC group). Healthy patients who had undergone one or more root canal treatments of the same type constituted the control group. The relationships of the following variables to survival and health status were examined (chi-squared test and multivariate analysis, P=0.05): age, gender, smoking habit, tooth location, treatment type, BPs treatment, BPs exposure, initial periapical index (PAI) and occlusal restoration. Survival curves were constructed using Kaplan–Meier analysis, with extraction serving as the end-point. Results: In total, 65 patients with 109 root canal-treated teeth who were taking BPs were included. At 60months, data from 57 patients (52F, 5M; median age 65.7±8.6years) who had undergone 96 root canal treatments were analysed (drop-out rate=16.9%). The survival rate was 85%, and the success rate was 76%. The control group consisted of 46 patients (21F, 25M; median age 60.3±7.2years) who had undergone 102 root canal treatments. The survival rate was 88%, with 12 teeth lost during follow-up. The success rate was 73%. In the BP group, 55 teeth were restored normally (OC group) and 41 teeth were restored at the tissue level (TL group). No difference in the success or survival rate was observed between the BP and control groups (P>0.05). Univariate Kaplan–Meier analysis revealed that only tooth type significantly affected survival status in the BP group. The analysis revealed the clinical relevance of smoking, tooth location and initial PAI on patients’ health status (P |
| Databáze: | OpenAIRE |
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