Compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronóstico

Autor:	Juan Carlos Roa S, Juan Carlos Araya O, Oscar Tapia E, Miguel Villaseca H
Rok vydání:	2011
Předmět:	medicine.medical_specialty genetic structures business.industry Stomach neoplasms Urology Cancer General Medicine Prognosis medicine.disease eye diseases Actuarial survival medicine.anatomical_structure Medicine In patient sense organs Risk factor business Lymph nodes Lymph node
Zdroj:	Revista médica de Chile v.139 n.8 2011 SciELO Chile CONICYT Chile instacron:CONICYT
ISSN:	0034-9887
DOI:	10.4067/s0034-98872011000800003
Popis:	Background : Extracapsular lymph node involvement has a negative prognosis in malignant tumors. Aim : To assess the prognostic importance of extracapsular lymph node involvement in patients with gastric cancer with lymph node metastases. Material and Methods: Clinical and morphological features and survival of patients with gastric cancer and lymph node involvement operated between 1986 and 2003, were analyzed. Patients with and without extracapsular involvement were compared. Results : During the study period, 459 gastrect omies were performed, 312 patients (68%) had lymph node involvement and 144 (31%) had extracapsular involvement. Patients with and without extracapsular involvem ent were followed for a median of 10 (range 1 to 120) and 41 (range 1 to 193) months, respectively. Five years actuarial survival for patients with and without extracapsular involvement was 23 and 40% respectively. Extracapsular lymph node in volvement and level of wall infi ltration were identifi ed as prognostic factors using a multivariate analysis. Conclusions : Extracapsular lymph node involvement is an independent risk factor for mortality among patients with gastric cancer
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460ccb357ba5111e46bd00dde7bdf53c https://doi.org/10.4067/s0034-98872011000800003 Zobrazit plný text záznamu