Gemcitabine-induced pseudocellulitis in a patient with non–small cell lung carcinoma
| Autor: | Erika E. Reid, Eseosa Asemota, Carrie L. Kovarik |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Pathology Nucleoside analogue Combination therapy business.industry gemcitabine chemotherapy Dermatology pseudocellulitis Rash Gastroenterology Hyperpigmentation Gemcitabine Carboplatin chemistry.chemical_compound noninfectious chemistry Internal medicine medicine Case Series medicine.symptom business Adverse effect medicine.drug Livedo reticularis |
| Zdroj: | JAAD Case Reports |
| ISSN: | 2352-5126 |
| Popis: | Gemcitabine (2,2-difluorodeoxycytidine) is a nucleoside analogue used as a chemotherapeutic agent to treat various malignancies. The common side effects of gemcitabine include myelosuppression, gastrointestinal disturbances, influenzalike symptoms, and elevation of liver enzyme levels. Gemcitabine is also associated with cutaneous adverse effects such as rash, alopecia, pruritus, radiation recall dermatitis, hypersensitivity reactions, hyperpigmentation, and erysipeloid reactions.1, 2, 3 There are also a few isolated cases of livedo reticularis, sclerodermalike changes, Sweet's syndrome, and toxic epidermal necrolysis.3 Rarely, gemcitabine is associated with pseudocellulitis, a nonnecrotizing inflammation of the dermis and subcutis from a noninfectious etiology, which could be confused clinically for cellulitis.1, 4 We report a case of recurrent gemcitabine-induced pseudocellulitis after the use of gemcitabine and carboplatin combination therapy. |
| Databáze: | OpenAIRE |
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