Moxibustion Treatment for Knee Osteoarthritis: A Multi-Centre,Non-Blinded, Randomised Controlled Trial on the Effectiveness and Safetyof the Moxibustion Treatment versus Usual Care in Knee OsteoarthritisPatients

Autor: Hyo-Ju Park, Min-Hee Lee, Sun-Mi Choi, So-Young Jung, Ho Sueb Song, Seung-Hoon Lee, Mi-Suk Shin, Jungeun Kim, Tae-Hun Kim, Kun Hyung Kim, Ae-Ran Kim, Hyeong-Jun Kim, Jung Won Kang, Hee-Jung Jung, Kyung-Won Kang, Jin-Bong Choi, Kwon Eui Hong, Joo-Hee Kim
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Male
Knee Joint
medicine.medical_treatment
lcsh:Medicine
Osteoarthritis
law.invention
Randomized controlled trial
Quality of life
law
Surveys and Questionnaires
Medicine and Health Sciences
Medicine
lcsh:Science
Musculoskeletal System
Pain Measurement
Multidisciplinary
Middle Aged
Osteoarthritis
Knee
Neurology
Ashi
Research Design
Female
Anatomy
Research Article
Adult
medicine.medical_specialty
Drug-Related Side Effects and Adverse Reactions
Clinical Research Design
Moxibustion
Pain
Research and Analysis Methods
Complementary and Alternative Medicine
Adverse Reactions
Rheumatology
Acupuncture
Pain Management
Humans
Clinical Trials
Adverse effect
Aged
Pharmacology
Health Care Policy
business.industry
Arthritis
lcsh:R
Beck Depression Inventory
Biology and Life Sciences
medicine.disease
Health Care
Physical therapy
Quality of Life
lcsh:Q
Clinical Medicine
business
Zdroj: PLOS ONE(9): 7
PLoS ONE
PLoS ONE, Vol 9, Iss 7, p e101973 (2014)
Popis: Introduction This study tested the effectiveness of moxibustion on pain and function in chronic knee osteoarthritis (KOA) and evaluated safety. Methods A multi-centre, non-blinded, parallel-group, randomised controlled trial compared moxibustion with usual care (UC) in KOA. 212 South Korean patients aged 40–70 were recruited from 2011–12, stratified by mild (Kellgren/Lawrence scale grades 0/1) and moderate-severe KOA (grades 2/3/4), and randomly allocated to moxibustion or UC for four weeks. Moxibustion involved burning mugwort devices over acupuncture and Ashi points in affected knee(s). UC was allowed. Korean Western Ontario and McMaster Universities Questionnaire (K-WOMAC), Short Form 36 Health Survey (SF-36v2), Beck Depression Inventory (BDI), physical performance test, pain numeric rating scale (NRS) and adverse events were evaluated at 5 and 13 weeks. K-WOMAC global score at 5 weeks was the primary outcome. Results 102 patients (73 mild, 29 moderate-severe) were allocated to moxibustion, 110 (77 mild, 33 moderate-severe) to UC. K-WOMAC global score (moxibustion 25.42+/−SD 19.26, UC 33.60+/−17.91, p
Databáze: OpenAIRE
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