Estimating a Preference-Based Single Index for the Impact of Weight on Quality of Life-Lite (IWQOL-Lite) Instrument from the SF-6D
| Autor: | G. Rhys Williams, Ronette L. Kolotkin, John Brazier, Ross D. Crosby |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
Male obesity Adolescent media_common.quotation_subject Gastric bypass Patient satisfaction Weight loss Surveys and Questionnaires Statistics medicine Humans health-related quality of life (HRQOL) Impact of Weight on Quality of Life-Lite (IWQOL-lite) Aged media_common Aged 80 and over Actuarial science Variables business.industry Health Policy Body Weight utility measure Public Health Environmental and Occupational Health Regression analysis Iwqol lite Middle Aged Regression Patient Satisfaction Quality of Life Regression Analysis Female medicine.symptom business Body mass index SF-6D |
| Zdroj: | Value in Health. 7:490-498 |
| ISSN: | 1098-3015 |
| DOI: | 10.1111/j.1524-4733.2004.74012.x |
| Popis: | Objective To facilitate economic evaluations of interventions for treating obesity, we estimated a preference-based single index for the Impact of Weight on Quality of Life-Lite (IWQOL-lite) instrument by mapping it onto the SF-6D preference-based index. Methods A heterogeneous sample of 1972 individuals, composed of community volunteers and participants in weight loss programs, clinical trials, and gastric bypass studies, completed the IWQOL-lite, an obesity-specific measure of health-related quality of life (HRQOL), and the SF-36, a generic measure of HRQOL converted into the preference-based SF-6D. Models of the relationship between the IWQOL-lite and SF-6D of increasing complexity were estimated by regression analyses. Results The best fitting model for predicting SF-6D index scores entered levels for each item as independent variables ( R 2 = 0.530 in the cross-validation sample, with a mean absolute error of 0.0976). This model (1) makes fewer assumptions than those using total score, dimension scores or item scores as dependent variables and (2) provides a robust unbiased estimate of a preference-based index from IWQOL-Lite data where a preference-based measure was not used. The addition of age and body mass index (BMI) led to a slight improvement in the model. Conclusions It is possible to facilitate economic evaluations using results obtained from disease-specific instruments using this approach. A weakness of this approach is that there may be aspects of the condition that have not been properly reflected in the SF-6D index. It is, however, useful when a preference-based measure has not been administered and when it would be impractical to conduct a full valuation survey. |
| Databáze: | OpenAIRE |
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