Rationale for Use of Tdap Booster Vaccines for Adolescent Immunization: Overview of Efficacy, Safety, and Clinical Use
| Autor: | William P. Hitchcock |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
0301 basic medicine
Pediatrics medicine.medical_specialty Diphtheria vaccine Adolescent Whooping Cough Vaccination schedule Immunization Secondary Disease Diphtheria-Tetanus-acellular Pertussis Vaccines Disease Outbreaks 03 medical and health sciences 0302 clinical medicine medicine Humans 030212 general & internal medicine Child Immunization Schedule Booster (rocketry) Immunization Programs Tetanus business.industry Incidence Diphtheria Incidence (epidemiology) Health Plan Implementation medicine.disease United States Primary Prevention 030104 developmental biology Immunization Pediatrics Perinatology and Child Health business medicine.drug |
| Zdroj: | Clinical Pediatrics. 45:785-794 |
| ISSN: | 1938-2707 0009-9228 |
| DOI: | 10.1177/0009922806295276 |
| Popis: | Pertussis is one of the only vaccine-preventable diseases with increasing incidence in the United States. The incidence of pertussis infection in adolescents is a growing concern; it can be a severe disease that may lead to significant morbidity and mortality when transmitted to susceptible populations (eg, infants). Experts have conceded that booster vaccination of adolescents may considerably decrease the incidence of pertussis infections in previously immunized, partially immunized, and nonimmunized populations. Studies in 2 tetanus, diphtheria, and acellular pertussis (Tdap) booster vaccines licensed by the Food and Drug Administration (FDA) have shown efficacy against pertussis disease and have demonstrated a safety profile comparable to tetanus and diphtheria vaccine (Td) in adolescents. Immunization schedules now include use of Tdap vaccines for preadolescent and adolescent populations to counter the increase in pertussis outbreaks. Challenges for clinicians include prompt recognition of pertussis symptoms, proper diagnosis using appropriate tools, and timely reporting of pertussis infections to surveillance bodies. Additional studies are needed to monitor trends of pertussis incidence after implementing the new vaccination schedule for adolescents. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|