Comorbidities of Obsessive and Compulsive Symptoms in Huntington's Disease

Autor: Anne-Catherine Bachoud-Lévi, Kelly Ormond, Lynn Raymond, Carissa Gehl, Francis Walker, Jane Paulsen
Rok vydání: 2010
Předmět:
Zdroj: Journal of Nervous & Mental Disease. 198:334-338
ISSN: 0022-3018
DOI: 10.1097/nmd.0b013e3181da852a
Popis: Although current reports document a high rate of obsessive and compulsive symptoms (O/Cs) in Huntington's disease (HD), there have been no studies published that have made an attempt to identify comorbidities of O/Cs in HD. We examined O/Cs in 1642 individuals with a diagnosis of HD. Of those endorsing significant O/Cs (27.2%), nearly one-quarter reported obtaining treatment for obsessive compulsive disorder. Individuals with HD and O/Cs were older, had poorer functioning, and a longer duration of illness than those without O/Cs. Individuals with HD and O/Cs endorsed significantly higher psychiatric comorbidities of depression, suicidal ideation, aggression, delusions, and hallucinations. Participants with the most severe O/Cs and worse performance on the Stroop task, a measure of executive function. Clinicians should be aware that patients with HD and O/Cs might have a somewhat different clinical picture from those without, and may require a specialized treatment plan.
Databáze: OpenAIRE