Babesia bovis: Vaccination of cattle against heterologous challenge with fractions of lysate from infected erythrocytes
| Autor: | B.V. Goodger, G. B. Mirre, M.A. Commins, I.G. Wright |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Immunodiffusion
Vaccines Erythrocytes Lysis General Veterinary biology Babesia Cattle Diseases Heterologous Babesia bovis General Medicine biology.organism_classification Virology Microbiology Vaccination Infectious Diseases Isoantibodies Sephadex Babesiosis Insect Science Chromatography Gel Animals Cattle Parasitology |
| Zdroj: | Zeitschrift f�r Parasitenkunde Parasitology Research. 70:321-329 |
| ISSN: | 1432-1955 0044-3255 |
| DOI: | 10.1007/bf00927818 |
| Popis: | The distilled water lysate of erythrocytes infected with Babesia bovis was separated by gel filtration on Sephadex G200. The void volume fraction or a pool of retained fractions which had immunodiffusion activity were injected into two groups of five cattle. These were challenged 2 weeks after the final vaccination with a heterologous strain of B. bovis. A control group of five cattle was similarly challenged. Two of the five control animals died from the challenge, whereas none of the vaccinated animals died. There were significant differences in parasitaemia and pathophysiological parameters between the vaccinated groups and the control group. |
| Databáze: | OpenAIRE |
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