Reproducibility of musculoskeletal ultrasound for determining monosodium urate deposition: Concordance between readers

Autor: Jonathan Samuels, Rennie G. Howard, Michael H. Pillinger, Christopher J. Swearingen, Soterios Gyftopoulos, Ralf G. Thiele
Rok vydání: 2011
Předmět:
Zdroj: Arthritis Care & Research. 63:1456-1462
ISSN: 2151-464X
DOI: 10.1002/acr.20527
Popis: The role of musculoskeletal ultrasound (MSK-US) in studying monosodium urate (MSU) deposition is rapidly evolving. As a relatively inexpensive imaging approach that does not involve exposure to radiation, MSK-US permits both dynamic assessment of joints, and identification of inflammation using power Doppler technology to show microvascular blood flow. In gout, MSK-US has been shown to detect various findings, from free-floating MSU crystals in the synovial fluid (“snowstorm appearance”) [1], to MSU crystal deposition on the superficial margin of the articular cartilage (“double contour” sign), to presence of clinical and subclinical tophaceous deposits and erosions [2]. Using power Doppler, one study showed evidence of persistent mild inflammation in patients with asymptomatic chronic tophaceous gout [3]. As compared to X-ray, MSK-US may detect findings in gout at an earlier stage, and with more sensitivity for detecting small (
Databáze: OpenAIRE