Automatic registration of postmortem brain slices to MRI reference volume

Autor: Helena C. Chui, C. Zarow, T.-S. Kim, W. Sungkarat, Manbir Singh
Rok vydání: 2003
Předmět:
Zdroj: 1999 IEEE Nuclear Science Symposium. Conference Record. 1999 Nuclear Science Symposium and Medical Imaging Conference (Cat. No.99CH37019).
DOI: 10.1109/nssmic.1999.842795
Popis: A new strategy to register each slice of the postmortem brain to anatomically corresponding in-vivo MRI slices is presented. The approach relies on a recursive reslicing of the FVIRI volume using non-linear polynomial transformations. Simulation studies to validate the approach and results using real data are presented. The results suggest the feasibility and practicability of second- and third-order polynomials to register postmortem images on a slice-by-slice basis to corresponding MRI sections. Using this method, it is possible to investigate the pathology of a disease through routinely acquired MRIs and postmortem brain images.
Databáze: OpenAIRE