Towards in vivo differentiation of brain tumor versus normal tissue by means of torsional resonators
| Autor: | Diethelm Johannsmann, Berthold Bode, Arne Langhoff, Konstantinos Mpoukouvalas, Oliver Kempski, Axel Heimann, Patra Charalampaki |
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| Přispěvatelé: | Publica |
| Rok vydání: | 2013 |
| Předmět: |
Torsional Resonators
Materials science acoustic sensor Piezoelectric sensor Quantitative Biology::Tissues and Organs Overtone Physics::Medical Physics Brain tumor Resonator Nuclear magnetic resonance In vivo otorhinolaryngologic diseases medicine neurosurgery Electrical and Electronic Engineering Instrumentation Bandwidth (signal processing) Metals and Alloys Resonance Condensed Matter Physics medicine.disease Surfaces Coatings and Films Electronic Optical and Magnetic Materials piezoelectric sensors sense organs Contact area Biomedical engineering |
| Zdroj: | Sensors and Actuators A: Physical. 190:25-31 |
| ISSN: | 0924-4247 |
| DOI: | 10.1016/j.sna.2012.10.039 |
| Popis: | It was tested to what extend torsional acoustic resonators can serve to in vivo differentiate between healthy and tumorous brain tissue. The resonators employed consist of crystalline quartz. They are cylindrically shaped. The resonance frequency at the fundamental is 78 kHz. The best correlation between the shifts of resonance frequency and resonance bandwidth, on the one hand, and the state of the tissue, on the other, was found when analyzing ratios of the shifts in resonance frequency and resonance bandwidth. These ratios are independent of contact area. Taking data on the fundamental mode as well as the third overtone further improved the efficiency and precision of the technique. These results suggest that torsional resonators can serve as diagnostic tools in neurosurgery. |
| Databáze: | OpenAIRE |
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