Regulatory roles of microRNAs in insect pests: prospective targets for insect pest control
| Autor: | Wei Dou, Qiang Zhang, Guy Smagghe, Clauvis Nji Tizi Taning, Jin-Jun Wang |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0106 biological sciences
Insecta Pesticide resistance Insect pest control media_common.quotation_subject Biomedical Engineering Bioengineering Computational biology Insect Biology 01 natural sciences 03 medical and health sciences chemistry.chemical_compound 010608 biotechnology microRNA Animals Antagomir Prospective Studies 030304 developmental biology media_common Regulation of gene expression 0303 health sciences business.industry fungi Pest control food and beverages MicroRNAs chemistry Pest Control PEST analysis business Biotechnology |
| Zdroj: | Current Opinion in Biotechnology. 70:158-166 |
| ISSN: | 0958-1669 |
| Popis: | At the post-transcriptional level, microRNAs (miRNAs) play an important role in the regulation of gene expression, thereby influencing the outcome of many biological processes in insects, such as development, reproduction, metamorphosis, immunity, and insecticide resistance. The alteration of miRNA expression by mimic/agomir or inhibitor/antagomir via injection/feeding can lead to pest developmental abnormalities, death, or reduced pesticide resistance, indicating that miRNAs are potential targets for pest control. This review provides an overview of recent advances in understanding the regulatory roles of miRNA in agricultural and public health insect pest, and further highlights the potential of miRNAs as prospective targets in pest control. |
| Databáze: | OpenAIRE |
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