Biosynthesis of conjugatable saccharidic moieties of GM2 and GM3 gangliosides by engineered E. coli
| Autor: | Eric Samain, Hugues Driguez, Lémonia Birikaki, Sébastien Fort, Tatiana Antoine, Marie-Pierre Dubois |
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| Přispěvatelé: | Centre de Recherches sur les Macromolécules Végétales (CERMAV), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF) |
| Jazyk: | angličtina |
| Rok vydání: | 2005 |
| Předmět: |
endocrine system
Stereochemistry Molecular Sequence Data Oligosaccharides G(M2) Ganglioside medicine.disease_cause Catalysis chemistry.chemical_compound Biosynthesis Carbohydrate Conformation Escherichia coli Materials Chemistry medicine G(M3) Ganglioside Glycosides ComputingMilieux_MISCELLANEOUS Chemistry Metals and Alloys General Chemistry N-Acetylneuraminic Acid Surfaces Coatings and Films Electronic Optical and Magnetic Materials Sialic acid carbohydrates (lipids) Carbohydrate Sequence Biochemistry Propargyl Ceramics and Composites lipids (amino acids peptides and proteins) Genetic Engineering Glycoconjugates |
| Zdroj: | Chemical Communications Chemical Communications, Royal Society of Chemistry, 2005, pp.2558-2560 |
| ISSN: | 1359-7345 1364-548X |
| Popis: | Oligosaccharidic moieties of GM(2) and GM(3) gangliosides bearing an allyl or a propargyl aglycon, are efficiently biosynthesized on the gram scale by growing metabolically engineered Escherichia coli cells in the presence of the corresponding lactoside acceptors and sialic acid. |
| Databáze: | OpenAIRE |
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